Incyte (NASDAQ:INCY) reported encouraging 24-week interim findings from its Phase 3 STOP-HS clinical trial program, evaluating povorcitinib, an oral JAK1 inhibitor, in adults with moderate to severe hidradenitis suppurativa (HS).
The study revealed that patients treated with povorcitinib experienced clinically significant and meaningful improvements through Week 24. Almost 60% of participants in both povorcitinib groups achieved HiSCR50, a primary measure of treatment response.
Patients also noted reductions in skin pain, starting as early as Week 3 and persisting throughout the trial.
The drug’s safety profile remained consistent with previous reports, and both dosing regimens were generally well tolerated.
These interim results highlight the potential of povorcitinib as an effective option for patients suffering from this difficult-to-treat inflammatory skin disorder.
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