ADVFN US – Market Content Editor

Shares of Viridian Therapeutics (NASDAQ:VRDN) dropped about 40% on Monday after the company released topline data from its Phase 3 REVEAL-1 study of elegrobart in patients with active thyroid eye disease, even though the treatment met its primary endpoint. The trial produced a highly statistically significant treatment effect. Patients receiving elegrobart every four weeks (Q4W)…

Neumora Therapeutics, Inc. (NASDAQ:NMRA) on Monday reported fourth-quarter results that came in ahead of analyst estimates. Despite the earnings beat, the company’s stock declined about 2.15% in premarket trading as investors assessed its cash position and ongoing pipeline developments. The clinical-stage biopharmaceutical company posted a quarterly loss of $0.35 per share, outperforming the analyst consensus…

Shares of Connect Biopharma Holdings Limited (NASDAQ:CNTB) climbed about 11% after the company released positive findings from several clinical studies evaluating rademikibart, its anti-interleukin-4-receptor alpha antibody. The company reported preliminary results from a Phase 1 clinical pharmacology trial showing that a single 300 mg intravenous dose of rademikibart, delivered via a two-minute IV push, produced…

Anavex Life Sciences Corp. (NASDAQ:AVXL) has withdrawn its application seeking marketing authorization in the European Union for blarcamesine as a treatment for early-stage Alzheimer’s disease, the company said. The biopharmaceutical group noted that discussions with the European Medicines Agency are ongoing as it works to address issues raised by the Committee for Medicinal Products for…

Shares of Roma Green Finance (NASDAQ:ROMA) soared about 35% after the company unveiled plans for a $100 million share repurchase program. The ESG and sustainability advisory firm said its board of directors approved the buyback initiative, which will run through December 31, 2028. Roma Green Finance currently has a market capitalization of roughly $375 million.…

Shares of United Therapeutics Corporation (NASDAQ:UTHR) climbed about 12% on Monday after the company reported that its pivotal TETON-1 study of Tyvaso successfully achieved its primary endpoint in patients with idiopathic pulmonary fibrosis (IPF). The inhaled therapy demonstrated clear superiority over placebo in improving absolute forced vital capacity, showing a treatment difference of 130.1 mL.…

Shares of Avis Budget Group (NASDAQ:CAR) dropped about 10% on Monday after the company disclosed that it had entered into an Equity Distribution Agreement with a group of major investment banks. Under the agreement, dated March 27, 2026, Avis Budget has the option to sell up to 5,000,000 shares of its common stock through a…

Royalty Pharma plc (NASDAQ:RPRX) said it has entered into a research and development co-funding agreement with Johnson & Johnson (NYSE:JNJ) valued at $500 million to support the development of JNJ-4804, an experimental treatment for autoimmune diseases. The funding will be provided over the 2026–2027 period. JNJ-4804 is described as a novel co-antibody therapy designed to…

Sight Sciences Inc. (NASDAQ:SGHT) has obtained a court order confirming a jury’s finding that Alcon Inc. willfully infringed three patents related to glaucoma treatment technology. The order was issued on March 27, 2026, by the U.S. District Court for the District of Delaware. The ruling grants Sight Sciences $34 million in damages. This includes $5.5…

Shares of Sysco Corp (NYSE:SYY) fell more than 2% in premarket trading on Monday after a Bloomberg report said the food distribution giant is close to acquiring family-owned Restaurant Depot in a transaction valued at about $29 billion, including debt. According to the report, Restaurant Depot shareholders would receive $21.6 billion in cash along with…