ADVFN US – Market Content Editor
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Stoke Therapeutics Shares Slide After Updated Phase 3 Timeline
Shares of Stoke Therapeutics (NASDAQ:STOK) fell about 18% after the company outlined revised timelines for its Phase 3 EMPEROR trial evaluating zorevunersen as a treatment for Dravet syndrome. The biotechnology company said it now expects to complete enrollment of 150 patients in the second quarter of 2026, with top-line data anticipated in mid-2027. Stoke also…
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Day One Biopharmaceuticals Shares Surge on Robust 2025 Revenue Outlook
Shares of Day One Biopharmaceuticals (NASDAQ:DAWN) jumped about 19% on Monday morning after the company released preliminary figures showing strong revenue growth for 2025 driven by its lead product, OJEMDA. The biopharmaceutical group said preliminary 2025 U.S. net product revenue for OJEMDA reached $155.4 million, representing year-on-year growth of 172%. Alongside the update, Day One…
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Planet Labs Shares Advance on Major Multi-Year Contract With Sweden
Planet Labs PBC (NYSE:PL) shares climbed around 5% on Monday after the Earth observation company disclosed a multi-year agreement with the Swedish Armed Forces valued in the low nine-figure range. Under the deal, Sweden will receive a comprehensive package of Planet’s satellite platforms, space-based data and situational awareness capabilities to support national defense, peacekeeping and…
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Urban Outfitters Shares Slide Despite Record Holiday-Period Sales
Urban Outfitters (NASDAQ:URBN) shares fell about 7% on Monday morning, even after the retailer reported record holiday sales for the two months ended December 31, 2025. The lifestyle retail group, which operates brands including Anthropologie, Free People and Urban Outfitters, said total company net sales rose 9% compared with the same period in 2024. Net…
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Akamai Shares Rally After Morgan Stanley Lifts Rating on Improving Growth Outlook
Shares of Akamai Technologies (NASDAQ:AKAM) rose about 4% in premarket trading after Morgan Stanley upgraded the stock twice, moving it to Overweight from Underweight, citing improving growth dynamics and an undemanding valuation. The bank said Akamai appears to be approaching an inflection point following several years of subdued growth, arguing that the current share price…
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American Eagle Shares Slide Despite Higher Q4 Operating Income Outlook
American Eagle Outfitters (NYSE:AEO) lifted its fourth-quarter operating income guidance after reporting strong holiday-season trading, but the update failed to reassure investors. Shares of the apparel retailer fell about 9.7% in premarket trading on Monday, despite the improved forecast. The company now expects fourth-quarter operating income to come in between $167 million and $170 million,…
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Lexeo Therapeutics Shares Slide Following PKP2 Gene Therapy Update
Shares of Lexeo Therapeutics (NASDAQ:LXEO) dropped about 17% on Monday after the company published interim Phase I/II results for its PKP2 gene therapy candidate, LX2020, being developed for PKP2-associated arrhythmogenic cardiomyopathy. The clinical-stage genetic medicine company said LX2020 was generally well tolerated in ten treated participants, with no clinically meaningful complement activation reported. The data…
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Abercrombie & Fitch Shares Slide After Higher Capex Guidance and Tighter Sales Outlook
Abercrombie & Fitch (NYSE:ANF) said it has lifted its full-year capital spending expectations while trimming and narrowing parts of its sales and margin guidance, prompting a pullback in the stock. Shares of the apparel retailer fell about 5.5% in premarket trading on Monday following the update. The company now forecasts full-year capital expenditure of roughly…
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Meta Platforms Appoints Dina Powell McCormick as President
Meta Platforms (NASDAQ:META) said on Monday that it has named Dina Powell McCormick as president and vice chair, marking a notable shift in the company’s senior leadership. The announcement comes only weeks after Powell McCormick stepped down from Meta’s board of directors, moving from a non-executive role into one of the company’s top management positions.…
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Dow Jones, S&P, Nasdaq, Wall Street, U.S. Futures Slide Further as Political Pressure Intensifies Around Fed Chair
U.S. equity index futures extended losses on Monday as concerns mounted over the independence of the Federal Reserve, following confirmation that the Justice Department has opened a criminal investigation into testimony by Fed Chair Jerome Powell regarding cost overruns tied to a $2.5 billion renovation of the central bank’s Washington headquarters. By 05:50 ET, Dow…