ADVFN US – Market Content Editor

Fulcrum Therapeutics (NASDAQ:FULC) soared 50% on Monday after unveiling upbeat preliminary findings from its Phase 1b PIONEER study evaluating pociredir in patients with sickle cell disease. The biotech reported that the 20 mg cohort delivered a strong increase in fetal hemoglobin (HbF). By Week 6, mean absolute HbF had risen 9.9%—notably higher than the 5.6%…

Agios Pharmaceuticals (NASDAQ:AGIO) dropped 7% after revealing that the U.S. Food and Drug Administration has yet to issue a ruling on its supplemental New Drug Application (sNDA) for mitapivat. The filing seeks expanded approval for mitapivat to treat adults with both non–transfusion-dependent and transfusion-dependent forms of alpha- and beta-thalassemia. Although the application cleared its Prescription…

Strategy Inc. (NASDAQ:MSTR) revealed on Dec. 8, 2025, that it bought an additional 10,624 Bitcoin (COIN:BTCUSD) between Dec. 1 and Dec. 7, spending roughly $962.7 million. The company said the purchases were executed at an average price of $90,615 per coin. The acquisition was funded through proceeds raised under Strategy’s at-the-market (ATM) equity offering program.…

Shares of Confluent Inc. (NASDAQ:CFLT) surged in premarket trading Monday after a Wall Street Journal report said International Business Machines (IBM) is close to sealing an $11 billion takeover of the data infrastructure company. By 06:15 ET, Confluent stock was up 28.1%. According to the report, the two sides could announce a deal as early…

Berkshire Hathaway Inc. (NYSE:BRK.B) unveiled a series of organizational changes as longtime chief executive Warren Buffett approaches his planned departure at the end of 2025. One of the most notable updates is the upcoming exit of Todd Combs, who has been both an investment manager at Berkshire and the CEO of GEICO. Combs will depart…

Eli Lilly’s (NYSE:LLY) blockbuster diabetes treatment Mounjaro is set to become part of China’s state medical insurance system beginning January 1, the National Healthcare Security Administration announced on Sunday. The decision means the once-weekly injectable will be reimbursable for adults with type 2 diabetes. Its inclusion is expected to broaden access across China’s population of…

Carvana (NYSE:CVNA) rallied 8.8% in premarket trading Monday after being selected for inclusion in the S&P 500 index. The move positions the online used-car retailer to extend its current 10-day winning streak. S&P Dow Jones Indices announced late Friday that Carvana will officially join the benchmark index on December 22. Carvana stock price

Fermi America (NASDAQ:FRMI) has finalized an electric service agreement with Southwestern Public Service Company, part of Xcel Energy, to provide the power needed for its Project Matador Campus in Amarillo, Texas. Under the deal, the utility will deliver up to 200 megawatts of capacity to the site, which is home to Fermi’s expanding artificial intelligence…